College football · all-time series
Michigan State vs. USC
Michigan State
Big Ten
USC
Big Ten4–5
9 meetings
Series leaderUSC by 1
Series span1963–2025
Current streakUSC 1
Largest marginUSC by 45
Score archive
Recent meetings
2025Sep 21, 2025
Michigan State31
USC45
Los Angeles Memorial Coliseum
1990Dec 31, 1990
USC16
Michigan State17
Neutral site
1987Jan 1, 1988
Michigan State20
USC17
Neutral site
1987Sep 7, 1987
USC13
Michigan State27
Michigan State home
1978Sep 29, 1978
Michigan State9
USC30
USC home
1972Sep 30, 1972
Michigan State6
USC51
USC home
1967Sep 30, 1967
USC21
Michigan State17
Michigan State home
1964Oct 3, 1964
USC7
Michigan State17
Michigan State home
1963Oct 4, 1963
Michigan State10
USC13
USC home